Living with Attention Deficit Hyperactivity Disorder (ADHD) presents unique challenges. Whether it is the struggle to maintain focus during a workday or the difficulty in regulating impulses, finding the right medication is often the key to unlocking your potential. While long-acting stimulants are a common starting point, many patients require more flexibility and precision in their treatment.
Amfexa tablets represent the gold standard in immediate-release ADHD medication. As the only UK-licensed brand of dexamfetamine sulphate, Amfexa offers a reliable, high-quality solution for adults and children (over 6 years) where other treatments, such as methylphenidate or lisdexamfetamine (Elvanse), have not provided sufficient symptom control.
At Online Meds UK, we are proud to stock the full range of Amfexa 5mg, 10mg, and 20mg tablets. Sourced directly from legitimate UK wholesalers and dispensed from our GPhC-registered pharmacy, you can buy Amfexa tablets UK with complete confidence. Our integrated private prescription service allows you to access this medication following a comprehensive assessment by our specialist prescribers.
What are Amfexa Tablets?
Amfexa is the branded formulation of dexamfetamine sulphate. Unlike generic dexamfetamine, which can vary in appearance and filler ingredients between manufacturers, Amfexa provides consistency—a crucial factor for sensitive patients.
- Active Ingredient: Dexamfetamine Sulphate.
- Class: Central Nervous System (CNS) Stimulant.
- Strengths Available:
- Amfexa 5mg: Ideal for titration (finding your dose) and for children.
- Amfexa 10mg: The standard adult maintenance unit.
- Amfexa 20mg: High-strength option for established patients, reducing the number of tablets needed.
How Amfexa Works: The Science of Stimulation
How Amfexa (dexamfetamine) works is rooted in neurobiology. In the ADHD brain, there is often a dysregulation of specific neurotransmitters—chemical messengers that help brain cells communicate. Specifically, levels of dopamine (linked to reward and motivation) and noradrenaline (linked to attention and alertness) may be lower than necessary for optimal executive function.
Amfexa acts as a releasing agent. It enters the neurons and promotes the release of these vital chemicals into the synapse.
- Improves Concentration: It “turns up the volume” on the brain’s focus networks, making it easier to stick to boring or complex tasks.
- Reduces Impulsivity: By strengthening the brain’s “brakes,” it helps filter out distractions and control impulsive behaviours.
- Rapid Onset: Unlike prodrugs (like Elvanse) which must be processed by the liver, Amfexa is active immediately. Patients typically feel the benefits within 30 to 60 minutes.
Why Choose Amfexa Over Generics or Elvanse?
Patients often ask about the difference between Amfexa vs Elvanse or generic dexamfetamine.
1. Precision Dosing
Elvanse (Lisdexamfetamine) is a “one-and-done” daily capsule lasting up to 13 hours. While convenient, this doesn’t suit everyone. Some patients find Elvanse wears off too early (the “afternoon crash”) or lasts too long (causing insomnia). Amfexa gives you control. You can take a dose in the morning for work, and a second dose in the afternoon if needed, or skip the afternoon dose to ensure you sleep well. It is also frequently prescribed as a “top-up” alongside Elvanse to extend coverage into the evening.
2. Tablet Consistency
Generic medications can change shape and filler content depending on what the pharmacy has in stock. Amfexa tablets UK are branded, meaning they are identical every time you order. This consistency is vital for patients who are sensitive to changes in their medication absorption.
3. Unique Strengths
Amfexa is available in a 20mg tablet, which is not always available in generic form (where patients often have to take four 5mg tablets). This makes adherence easier for those on higher doses.

Dosage and Administration
Correct usage is essential for safety and efficacy. Always follow the instructions provided by our prescribers.
- Starting Dose: Treatment is usually initiated at a low dose (e.g., 5mg once or twice daily) and increased weekly in 5mg increments.
- Frequency: Because it lasts 4-6 hours, Amfexa is typically taken 2 to 4 times a day.
- Example Schedule: 8:00 AM (upon waking) and 12:00 PM (before lunch).
- Swallowing: The tablets are scored and can be divided (except the 5mg in some packs) to fine-tune the dose. Swallow with water, with or without food.
- Late Doses: Avoid taking Amfexa after 4:00 PM unless explicitly directed, as it can cause significant insomnia.
Safety, Side Effects, and Warnings
As a Schedule 2 Controlled Drug, Amfexa is potent and must be used responsibly.
Common Side Effects
- Reduced Appetite: This is very common. It is important to eat a good breakfast before taking the medication and to monitor weight.
- Insomnia: Difficulty sleeping if taken too late in the day.
- Dry Mouth: Stay hydrated.
- Palpitations: Mild increases in heart rate are common, but chest pain should be reported immediately.
Contraindications
- Cardiovascular Disease: Not suitable for patients with structural heart defects, severe hypertension, or arrhythmias.
- Psychiatric History: Use with caution in patients with a history of psychosis or bipolar disorder, as stimulants can exacerbate these conditions.
- Pregnancy: generally avoided unless the benefit outweighs the risk.
Driving Laws
It is legal to drive on Amfexa in the UK if you have a prescription and your driving is not impaired. You should carry your prescription or the medicine box with you in the car.
Ordering from Online Meds UK
We have simplified the process of obtaining this specialist medication while maintaining the highest clinical standards.
- Consultation: Complete our free online medical questionnaire. You will be asked about your ADHD diagnosis, current medications, and heart health.
- Verification: Our UK-registered prescribers review your details. We may check the National Summary Care Record or contact your GP to verify your diagnosis and safety status (with your consent).
- Dispensing: Once approved, your Amfexa 5mg, 10mg, or 20mg is dispensed by our pharmacists.
- Delivery: Sent via Royal Mail Special Delivery (tracked and signed for) in plain packaging to ensure privacy and security.
Frequently Asked Questions (FAQs)
- Is Amfexa the same as Adderall?
No. Adderall (common in the USA) is a mixture of amphetamine salts (amphetamine + dexamfetamine). Amfexa contains only pure dexamfetamine. However, they are very similar in effects and potency. Adderall is not licensed in the UK; Amfexa is the closest licensed equivalent. - Can I take Amfexa with Elvanse?
Yes, this is a very common combination. Many patients take Elvanse in the morning and a small dose of Amfexa 5mg or 10mg in the afternoon as a “booster” when the Elvanse wears off, to help with the evening commute or household tasks. This must be authorised by your prescriber. - Do I need an NHS prescription to buy from you?
No. You do not need a physical paper prescription from your GP. Our online service includes a private prescription issuance (if you are eligible). However, you must have a confirmed diagnosis of ADHD to be prescribed this medication. - Is Amfexa addictive?
When taken as prescribed for ADHD, the risk of addiction is low. The slow oral release and therapeutic dosing differ significantly from recreational misuse. However, it is a controlled substance, and you should never share your medication with others. - What is the maximum dose?
The maximum licensed daily dose in the UK is typically 60mg for adults, though this varies based on individual tolerance and medical history. Most patients stabilise on between 20mg and 40mg per day.
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