When standard painkillers like ibuprofen or plain paracetamol are not enough to manage your discomfort, co-codamol 30/500mg offers a stepped-up solution. As one of the most widely prescribed analgesics in the country, this medication provides robust relief by combining two active ingredients into a single, convenient tablet.
We offer genuine co-codamol 30/500mg tablets sourced directly from UK-licensed wholesalers. As a GPhC-registered pharmacy, we ensure that every order is reviewed by a qualified prescriber to ensure it is safe for you. If appropriate, you can buy co-codamol 30/500mg UK legally through our service without needing an existing NHS prescription, thanks to our integrated private prescription service.
What is Co-codamol?
Co-codamol tablets are a compound analgesic. They contain two distinct medicines that work together (synergistically) to relieve pain:
- Paracetamol (500mg): An antipyretic and analgesic that lowers fever and reduces pain intensity.
- Codeine Phosphate (30mg): An opioid combination analgesic that binds to receptors in the brain to block pain signals.
The “30/500” strength indicates the highest strength of codeine available in this combination (30mg) alongside the standard dose of paracetamol (500mg). This makes it significantly stronger than the “8/500” version available over the counter.
How Co-codamol Works for Pain Relief
Understanding how co-codamol works for pain relief requires looking at its dual mechanism. Paracetamol works primarily by inhibiting the production of prostaglandins in the brain—chemicals that cause inflammation and swelling. Simultaneously, the codeine component converts into morphine in the liver, which then blocks pain messages from travelling along the nerves to the brain.
This multi-modal approach is why codeine paracetamol combination explained in clinical terms is often more effective than taking either medication alone. It is particularly effective for:
- Severe toothache.
- Muscular and rheumatic pain.
- Post-operative pain.
- Migraine or severe headache.
Dosage and Administration
It is vital to follow strict co-codamol 30/500mg dosage information to avoid liver damage from paracetamol or respiratory issues from codeine.
- Adults and children over 12 years: Swallow 1 or 2 tablets every 4 to 6 hours as needed.
- Maximum Dose: Do not take more than 8 tablets (which equals 4g of paracetamol and 240mg of codeine) in any 24-hour period.
- Duration: This medication is for short-term use only (maximum 3 days) unless explicitly directed otherwise by a doctor.
Safety, Side Effects, and Contraindications
As with all opioids, co-codamol side effects and safety must be taken seriously.
- Common Side Effects: Constipation, nausea, drowsiness, and dizziness.
- Driving: Because it can cause drowsiness, you must follow UK drug-driving laws. Do not drive if your ability is impaired.
- Contraindications: Do not take this if you are already taking other medicines containing paracetamol (e.g., cold and flu remedies) to avoid overdose. Co-codamol contraindications also include acute asthma, respiratory depression, or known hypersensitivity to opioids.
Co-codamol vs. Codeine Phosphate
Patients often ask about the difference between co-codamol vs codeine phosphate.
- Co-codamol: Contains both paracetamol and codeine. It attacks pain from two angles but carries the risk of paracetamol toxicity if overdosed.
- Codeine Phosphate: Contains only codeine. It allows you to take ibuprofen or paracetamol separately if you wish, offering more flexibility in dosing. However, for many, the convenience of the single co-codamol UK tablet is preferred for managing acute flare-ups.

Co-codamol
Legal Information and Prescribing Guidance
Co-codamol prescribing guidance UK classifies the 30/500mg strength as a Prescription Only Medicine (POM). It is also subject to co-codamol controlled drug UK regulations (Schedule 5) due to the codeine content.
- Addiction Warning: Codeine is an addictive substance. Regular use for more than 3 days can lead to tolerance and addiction.
- Withdrawal: Stopping abruptly after long-term use can cause restlessness and irritability.
Our pharmacists provide a comprehensive co-codamol patient information leaflet with every order, detailing co-codamol use guidelines UK and co-codamol drug interactions (such as avoiding alcohol or benzodiazepines while on treatment).
Frequently Asked Questions (FAQs)
- Can I buy co-codamol 30/500mg UK over the counter?
No. You can buy lower strengths (8/500mg) over the counter, but the stronger co-codamol 30/500mg is a Prescription Only Medicine. You can order it from us after completing a quick online consultation which is reviewed by our prescribers. - Is co-codamol good for moderate pain UK?
Yes, co-codamol for moderate pain UK is the standard “Step 2” treatment on the analgesic ladder. It is designed for pain that is not relieved by aspirin, ibuprofen, or paracetamol alone. - Can I take ibuprofen with co-codamol?
Yes, you can usually take ibuprofen alongside co-codamol, provided you do not have stomach issues (like ulcers) or asthma that is triggered by NSAIDs. Do not take plain paracetamol with co-codamol, as it already contains a full dose of paracetamol. - How long does it take to work?
The effects typically start within 30 to 60 minutes and last for up to 4 to 6 hours. - What are the signs of overdose?
Because of the paracetamol content, overdose is dangerous and can be fatal (liver failure). Immediate medical attention is required even if you feel well initially. Never exceed the stated dose.
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